Recruitment and Assessment Core
Specific Aims for the Recruitment and Assessment Core
(1) To provide timely recruitment and standardized assessments for all NeuroMAP projects
(2) To maintain a reproducible and reliable assessment structure that can be used for extramurally supported projects
(3) To develop a self-sustainable business plan for the user base.
Services Available to Internal and External Investigators
(1) Consultation concerning recruitment and assessment strategies from the Core Director or Core Team Manager
(2) Research Assessment services at the below tiers of service:
Contact Dr. Rayus Kuplicki for more information about these services and their costs.
(1) To provide timely recruitment and standardized assessments for all NeuroMAP projects
(2) To maintain a reproducible and reliable assessment structure that can be used for extramurally supported projects
(3) To develop a self-sustainable business plan for the user base.
Services Available to Internal and External Investigators
(1) Consultation concerning recruitment and assessment strategies from the Core Director or Core Team Manager
(2) Research Assessment services at the below tiers of service:
- Tier 1, Research Assistant (e.g., non-clinical surveys/behavioral measures)
- Tier 2, Medical Technician (e.g., blood draws/vital sign measurements)
- Tier 3, Registered Nurse (e.g., medical/physiological assessments)
- Tier 4, Clinical Interviewer (e.g., diagnostic assessments and clinical ratings)
- Tier 5, Physician (e.g., diagnostic assessment, physical/mental status exam)
Contact Dr. Rayus Kuplicki for more information about these services and their costs.
Circuits and Molecules Core
Specific Aims for the Circuits and Molecules Core
(1) To provide state-of-the-art disease-modifying processes (DMP)-focused neuroimaging assessments for all NeuroMAP projects
(2) To provide state-of-the-art DMP-focused laboratory assessments for all NeuroMAP projects
(3) To develop a self-sustainable business plan for the user base
CIRCUITS CORE
Services
Contact Dr. Michael Rohan for more information about these services and their costs.
MOLECULES CORE
The Molecules Core houses four laboratory rooms dedicated to human blood processing, specimen long-term biobanking, bioassays, and extracellular vesicle (EV) research.
Services
A formal request should be submitted in writing to Dr. Jonathan Savitz to request the use of NeuroMAP blood samples. The request should include a concise summary of the proposed study including aims, hypotheses, rationale, details of experiments planned, and the type and volume of samples needed. Only one aliquot per subject/time point is allowed per project.
Contact Dr. Kaiping Burrows for more information about these services and their costs.
(1) To provide state-of-the-art disease-modifying processes (DMP)-focused neuroimaging assessments for all NeuroMAP projects
(2) To provide state-of-the-art DMP-focused laboratory assessments for all NeuroMAP projects
(3) To develop a self-sustainable business plan for the user base
CIRCUITS CORE
Services
- Acquire structural, functional, and tissue-characterizing magnetic resonance imaging at the LIBR MRI Facility
- Acquire physiological data acquired during MR experiments, and subject response data acquired during behavioral tasks in the magnet
- Acquire EEG data simultaneously with fMRI data
- Acquire blood samples from research subjects
- Acquire and manage clinical overread scans for subject safety
- Deliver data from these data acquisitions
Contact Dr. Michael Rohan for more information about these services and their costs.
MOLECULES CORE
The Molecules Core houses four laboratory rooms dedicated to human blood processing, specimen long-term biobanking, bioassays, and extracellular vesicle (EV) research.
Services
- Blood processing - serum, plasma, and peripheral blood mononuclear cells (PBMCs)
- Specimen biobanking for long-term storage
- Enzyme-linked immunosorbent assay (ELISA)
- RNA/DNA/Protein extraction
- Extracellular vesicles (EV) isolation
- Brain-enriched EV isolation
A formal request should be submitted in writing to Dr. Jonathan Savitz to request the use of NeuroMAP blood samples. The request should include a concise summary of the proposed study including aims, hypotheses, rationale, details of experiments planned, and the type and volume of samples needed. Only one aliquot per subject/time point is allowed per project.
Contact Dr. Kaiping Burrows for more information about these services and their costs.
Data Management and Statistics Core
Specific Aims for the Data Management and Statistics Core
(1) To provide data management and programming for all NeuroMAP projects
(2) To implement multilevel models, causal inference analyses and machine learning prediction algorithms
(3) To develop a self-sustainable business plan for the user base
Services
Contact Dr. Rayus Kuplicki for more information about these services and their costs.
(1) To provide data management and programming for all NeuroMAP projects
(2) To implement multilevel models, causal inference analyses and machine learning prediction algorithms
(3) To develop a self-sustainable business plan for the user base
Services
- Tier 1, Senior Statistics - Senior level statistical consultation, analysis, and grant support.
- Tier 2, Neuroimaging and Data Management - Management of neuroimaging, behavioral, and psychophysiological data to create BIDS formatted datasets as well as subsequent first and second level analysis support.
- Tier 3, General Programming and Analysis - Implementation of behavioral tasks, bioinformatics, statistical modeling, and submission to public repositories like NDA to satisfy data sharing requirements.
Contact Dr. Rayus Kuplicki for more information about these services and their costs.
For general questions about LIBR Core Services, please contact Rachael Gotcher at [email protected].